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ABclonal Technology PerCP Rabbit anti-Human CD68
Supplier: ABclonal Technology A26255200T
This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages It is a member of the lysosomal endosomal-associated membrane glycoprotein (LAMP) family The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins The protein is also a member of the scavenger receptor family Scavenger receptors typically function to clear cellular debris promote phagocytosis and mediate the recruitment and activation of macrophages Alternative splicing results in multiple transcripts encoding different isoforms
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