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Apexbio Technology LLC Perindopril 82834-16-0 1g
Supplier: Apexbio Technology LLC B12141000
Perindopril (CAS 82834-16-0) is an inhibitor of angiotensin I-converting enzyme (ACE) widely used in biomedical research By blocking ACE activity Perindopril suppresses the formation of angiotensin II a peptide involved in vasoconstriction and angiogenesis In cancer studies Perindopril has demonstrated the ability to inhibit tumor growth and angiogenesis in head and neck squamous cell carcinoma models While it does not significantly affect cell proliferation in vitro it reduces VEGF mRNA expression and promoter activity at concentrations as low as 1 M In vivo Perindopril has been shown to suppress tumor growth and lower blood pressure without altering heart rate supporting its application in oncology and cardiovascular research
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