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AdipoGen Periostin mAb blockOC-20
Supplier: AdipoGen AG20B6000YPFC500
Monoclonal Antibody. Isotype Mouse IgMkappa.Immunogen Recombinant fragments of human periostin.. Application FUNC Blocking, ICC. Liquid. In PBS. Recombinant fragments of human periostin. Periostin is a 90-kDa matricellular protein that consists of a typical signal sequence, followed by a cysteine-rich region, an EMI domain protein-protein interactions, four tandem fasciclin-like domains that are responsible for integrin binding, and a C-terminal region. Periostin was originally isolated as an osteoblast-specific factor that functions as a cell adhesion molecule for pre-osteoblasts and in osteoblast recruitment, attachment and spreading. Periostin is also involved in many fundamental biological processes such as cell proliferation, cell invasion and angiogenesis. Periostin expression is increased by both transforming growth factor beta1 TGF-beta1 and bone morphogenetic protein 2 BMP-2.
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