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AdipoGen anti-Periostin, mAb (Stiny-1) (preservative free) (100 µg)
Supplier: AdipoGen AG20B0033PFC100
Monoclonal Antibody. Recognizes human and mouse periostin. Isotype: Mouse IgG1kappa. Clone: Stiny-1. Applications: ELISA, IHC, WB. Liquid. In PBS containing 10% glycerol. Periostin is involved in many fundamental biological processes such as cell proliferation, cell invasion and angiogenesis. Periostin expression is increased by both transforming growth factor beta1 (TGF-beta1) and bone morphogenetic protein 2 (BMP-2). Changes in periostin expression are commonly detected in various cancers and pre-cancerous conditions, and periostin may be involved in regulating cancer cell activities that contribute to tumorigenesis, cancer progression and metastasis. Periostin has shown to be involved in many aspects of allergic inflammation, such as eosinophil recruitment, airway remodeling, development of a Th2 phenotype and increased expression of inflammatory mediators. It is evaluated as a biomarker for bronchial asthma and airway inflammation.
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