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Cayman Chemical Periplogenin 10MG
Supplier: Cayman Chemical 3504710 MG
A cardenolide and an active metabolite of periplocin with diverse biological activities; reduces the activity of porcine Na+/K+ ATPase at 0.3 or 0.6 µM; induces apoptosis in U937 and PC3 prostate cancer cells, as well as inhibits the proliferation of these cells (EC50s = 1.41 and 1.2 µM, respectively) at 0.1 or 0.2 µM; increases ROS production and induces necroptosis in HaCaT keratinocytes at 2 UG/ml; reduces EAr thickness in a mouse model of TPA-induced psoriasis
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