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Medchemexpress LLC Pexidartinib hydrochloride | 2040295-03-0 | 99.77% | 454.28 | 1 ML
Supplier: Medchemexpress LLC HY16749A10MM/1ML
Pexidartinib hydrochloride is a potent, orally active, selective, and ATP-competitive inhibitor of colony stimulating factor 1 receptor (CSF1R or M-CSFR) and c-Kit. It exhibits high selectivity for c-Kit and CSF1R over other related kinases, induces cell apoptosis, and demonstrates anti-cancer activity.
- Potent, orally active, selective, and ATP-competitive inhibitor
- Induces cell apoptosis
- Demonstrates anti-cancer activity
- High selectivity for c-Kit and CSF1R over other related kinases
- Can be used to deplete microglia cells in mice
- Reduces tissue macrophage levels
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