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Medchemexpress LLC Pexidartinib hydrochloride | 2040295-03-0 | 99.8% | 454.28 | 200 MG
Supplier: Medchemexpress LLC HY16749A200MG
Pexidartinib hydrochloride is a potent, orally active, selective, and ATP-competitive inhibitor of colony stimulating factor 1 receptor (CSF1R or M-CSFR) and c-Kit. This compound induces cell apoptosis and demonstrates anti-cancer activity.
- Potent, orally active, selective, and ATP-competitive inhibitor.
- Targets colony stimulating factor 1 receptor (CSF1R) and c-Kit.
- Exhibits high selectivity over other related kinases.
- Induces cell apoptosis and demonstrates anti-cancer activity.
- IC50 of 10 nM for c-Kit and 20 nM for cFMS.
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