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Cayman Chemical PF-04691502 50mg
SDP

Catalog No. 502969238
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A PI3Kα, -β, -δ, -γ, and mTOR inhibitor (Kis = 1.8, 2.1, 1.6, 1.9, and 16 nM, respectively, for the human enzymes); decreases the proliferation of BT-20, SKOV3, and U87MG cells (IC50s = 313, 188, and 179 nM, respectively); inhibits capillary tube formation by, and migration of, HUVECs at 2.5 and 5 µM; induces cell cycle arrest at the G1 phase in U87MG cells at 500 and 1,000 nM; decreases tumor volume in NCI H1650 and H1975 NSCLC mouse xenograft models at 10 mg/kg per day

Catalog No. 50-296-9238 Supplier Cayman Chemical Supplier No. 1501750 MG
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A PI3Kα, -β, -δ, -γ, and mTOR inhibitor (Kis = 1.8, 2.1, 1.6, 1.9, and 16 nM, respectively, for the human enzymes); decreases the proliferation of BT-20, SKOV3, and U87MG cells (IC50s = 313, 188, and 179 nM, respectively); inhibits capillary tube formation by, and migration of, HUVECs at 2.5 and 5 µM; induces cell cycle arrest at the G1 phase in U87MG cells at 500 and 1,000 nM; decreases tumor volume in NCI H1650 and H1975 NSCLC mouse xenograft models at 10 mg/kg per day

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