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Cayman Chemical PF-04708671 50mg

Supplier: Cayman Chemical 1501850 MG

A vitamin A metabolite and RAR ligand (IC50s 9 3 and 10 nM for RARa RARB and RARY respectively) induces expression of a luciferase reporter in COS-7 cells expressing RARa RARB or RARY (EC50s 169 9 and 2 nM respectively) reduces TPA-induced papilloma formation in mice at 17 nmol reduces bile duct proliferation hydroxyproline levels and liver inflammation in a rat model of a-naphthylisothiocyanate-induced chronic cholestasis reduces plasma levels of alkaline phosphatase and bile salts in the Mdr2-/- mouse model of cholestasis reduces hepatic fat accumulation triglycerides body weight and serum glucose levels in mice with Western diet-induced obesity
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