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Medchemexpress LLC PF-06456384 trihydrochloride | 1834610-75-1 | ≥98.0% | 829.18 g·mol⁻¹ | C35H32F3N7O3S2 · 3HCl | 25 MG
Supplier: Medchemexpress LLC HY118952A25MG
The trihydrochloride salt is a small-molecule research compound described as a highly potent and selective inhibitor of the NaV1.7 voltage-gated sodium channel; it has reported sub-nanomolar activity and is used in preclinical pain model research.
- Highly potent and selective NaV1.7 inhibition (reported IC50 ≈ 0.01 nM).
- Used in preclinical pain models, including the formalin test.
- Supplied as a trihydrochloride salt in white to beige powder form.
- High purity (≥98% by HPLC reported by distributors).
- Solubility: readily soluble in DMSO (~125 mg/mL); limited aqueous solubility (~2 mg/mL reported).
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