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Medchemexpress LLC Pf-06815345 (hydrochloride) | 2334434-49-8 | 98.15% | 634.49 | 25 MG
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Supplier:  Medchemexpress LLC 25MGHY112598A

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PF-06815345 hydrochloride is an orally active and potent inhibitor of proprotein convertase subtilisin/kexin type 9 (PCSK9) with an IC50 value of 13.4 μM. It significantly decreases the PCSK9 level in vivo in mouse.

  • Orally active.
  • Potent inhibitor of proprotein convertase subtilisin/kexin type 9 (PCSK9).
  • Has an IC50 value of 13.4 μM for PCSK9 inhibition.
  • Significantly decreases PCSK9 levels in vivo in mice.
  • Lowers plasma PCSK9 to 72% at 500 mg/kg 4 hours after treatment in a humanized PCSK9 mouse model.

Catalog No. 50-004-39171


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