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Selleck Chemical LLC PF-06873600 S8816-5MG
Supplier: Selleck Chemical LLC S88165MG
PF-06873600 is an inhibitor of cyclin-dependent kinase 2 (CDK2) CDK4 and CDK6 with Ki values of 0 1 1 2 and 0 1 nM respectively blocks the phosphorylation of retinoblastoma protein (RB1) and limits the proliferation of OVCAR-3 ovarian cancer cells with EC50s of 19 and 45 nM respectively
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