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Medchemexpress LLC PF-07038124 hydrochloride | 2415317-57-4 | 99.3% | C18H23BClNO4 | 1 MG
Supplier: Medchemexpress LLC HY144683A1MG
PF-07038124 hydrochloride is a potent PDE4 inhibitor with an IC50 of 0.5 nM for PDE4B2. It demonstrates immunomodulatory effects by inhibiting IL-13, IL4, and IFNγ, making it suitable for research related to atopic dermatitis and plaque psoriasis. This compound has been investigated in Phase 1 and Phase 2 clinical trials for these conditions. It is supplied as an off-white to light yellow solid.
- Specifically targets PDE4B2 with high potency
- Shows inhibitory activity against IL-13, IL4, and IFNγ
- Used in the study of atopic dermatitis and plaque psoriasis
- Investigated in Phase 1 and Phase 2 clinical trials
- Soluble in DMSO at 100 mg/mL
- Recommended storage is 4°C sealed, away from moisture
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