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Selleck Chemical LLC PF-4708671 10mg 1255517-76-0
Supplier: Selleck Chemical LLC S216310MG
PF-4708671 is a cell-permeable inhibitor of p70 ribosomal S6 kinase (S6K1 isoform) with Ki/IC50 of 20 nM/160 nM in cell-free assays, 400-fold greater selectivity for S6K1 than S6K2, and 4- and >20-fold selectivity for S6K1 than MSK1 and RSK1/2, respectively. PF-4708671 induces autophagy. First S6K1-specific inhibitor to be reported. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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