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Apexbio Technology LLC PF-543 Citrate 1415562-83-2 200mg

Supplier: Apexbio Technology LLC A3718200
PF-543 Citrate (CAS 1415562-83-2) is a cell-permeable small molecule that functions as a potent and selective inhibitor of sphingosine kinase 1 (SphK1) It acts by competitively inhibiting sphingosine binding exhibiting a K(i) of 3 6 nM for SphK1 and demonstrating over 100-fold selectivity compared to the SphK2 isoform PF-543 Citrate is utilized in research to elucidate the specific contributions of SphK1-mediated sphingosine-1-phosphate (S1P) signaling in cellular and physiological processes
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