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Medchemexpress LLC HY-19999A 5mg Medchemexpress, PF-CBP1 hydrochloride CAS:2070014-93-4 Purity:>98%
Supplier: Medchemexpress LLC HY19999A5MG
Medchemexpress, HY-19999A 5mg PF-CBP1 hydrochloride CAS:2070014-93-4 PF-CBP1 hydrochloride is a highly selective inhibitor of the CREB binding protein bromodomain (CBP BRD). PF-CBP1 inhibits CREBBP and EP300 bromodomains with IC50 of 125 nM and 363 nM respectively. PF-CBP1 hydrochloride reduces LPS-induced inflammatory cytokines expression (IL-1β, IL-6 and IFN-β) in primary macrophages. PF-CBP1 hydrochloride also downregulates RGS4 expression cortical neurons and can be used for the research of neurological disorders, including epilepsy and parkinson's disease, et al. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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