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Medchemexpress LLC PH-797804 | 586379-66-0 | 98.9% | 477.30 g·mol⁻¹ | C22H19BrF2N2O3 | 200 MG
Supplier: Medchemexpress LLC HY10403200MG
PH-797804 is an ATP-competitive, selective inhibitor of p38 mitogen-activated protein kinases (p38α/p38β) used in research to probe p38-mediated signaling and inflammatory responses. It shows nanomolar biochemical potency and demonstrable cellular activity that reduces LPS-induced cytokine production.
- Selective ATP-competitive p38α/p38β inhibitor.
- Nanomolar biochemical potency (p38α IC50 26 nM; Ki 5.8 nM).
- Demonstrated cellular activity reducing LPS-induced TNF-α and IL-1β release.
- Does not inhibit JNK2, supporting target selectivity.
- High supplied purity and solid white to off-white appearance.
- Suitable for biochemical and cellular assay applications.
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