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Sigma Aldrich Fine Chemicals Biosciences Phalloidin fluorescein Iso1MG
Supplier: Sigma Aldrich Fine Chemicals Biosciences P5282.1MG
Phalloidin is a phallotoxin produced by death cap mushroom Amanita phalloides. It is a cyclic peptide which interacts with actin and this was first identified in phalloidin-poisoned rats. It is a heptapeptide cyclic in nature with a crosslink between tryptophan at position 6 and cysteine at position 3. The side chain of amino acid 7 (I3-δ-dihydroxyleucine) in phalloidin is accessible to modifications through which fluorescently labelled phalloidin compounds can be produced.
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