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Bachem (Phe13,Tyr19)-MCH (human, mouse, rat) Trifluoroacetate

Supplier: Bachem 4026028.1000

(Phe13,Tyr19)-MCH (human, mouse, rat) Trifluoroacetate, H-Asp-Phe-Asp-Met-Leu-Arg-Cys-Met-Leu-Gly-Arg-Val-Phe-Arg-Pro-Cys-Trp-Gln-Tyr-OH, 160201-86-5, C109H160N30O26S4, Mr 2434.92, 1mg. (Phe13,Tyr19)-Melanin-Concentrating Hormone (MCH) (human, mouse, rat). This derivative suitable for iodination is a further development of natural MCH, which loses its activity upon iodination. The labeled compound enabled to establish the first radioreceptor assay for MCH. Saturation binding experiments with this peptide, radioiodinated, revealed a Bmax of 1090 and a Kd of 1 · 10-10M for receptors in G4F-7 mouse melanoma cells.
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