Phellodendrine chloride (CAS No 104112-82-5) is a quaternary ammonium alkaloid primarily researched within the pharmacological and biochemical domains It originates from the bark of Phellodendron species and exhibits a variety of biological activities Its mechanism of action involves modulating pathways related to anti-inflammatory and neuroprotective effects often interacting with specific neurotransmitter receptors and ion channels In vitro studies demonstrate activity typically in the nanomolar to low micromolar range Phellodendrine chloride is widely applied in cell model studies to investigate its effects on neuronal and immune cells as well as in animal studies focusing on anti-inflammatory and cognitive function Additionally it serves as a candidate in drug screening for therapeutic agents targeting inflammation and neurodegenerative diseases Experimental concentrations typically depend on the specific research design