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Medchemexpress LLC HY-108464A 5mg Medchemexpress, Phenamil (methanesulfonate) CAS:1161-94-0 Purity:>98%
Supplier: Medchemexpress LLC HY108464A5MG
Medchemexpress, HY-108464A 5mg Phenamil (methanesulfonate) CAS:1161-94-0 Phenamil methanesulfonate, an analog of Amiloride (HY-B0285), is a more potent and less reversible epithelial sodium channel (ENaC) blocker with an IC50 of 400 nM. Phenamil methanesulfonate is also a competive inhibitor of TRPP3 and inhibits TRPP3-mediated Ca2+ transport with an IC50 of 140 nM in a Ca2+ uptake assay. Phenamil methanesulfonate is an intriguing small molecule to promote bone repair by strongly activating BMP signaling pathway[4]. Phenamil methanesulfonate is used for the research of cystic fibrosis lung disease[5]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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