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Medchemexpress LLC Phenazine-1-carboxylic acid | 2538-68-3 | 100.0% | 224.22 | 1 G
Supplier: Medchemexpress LLC HY330371G
Phenazine-1-carboxylic acid is an antifungal agent that also exhibits anticancer activity by inducing apoptosis in cancer cells through the regulation of ROS generation. It can upregulate the expression of IL-8 and ICAM-1 while inhibiting the release of RANTES and MCP-1, demonstrating its potential immunomodulatory effects. It holds significant research value in anti-infection, anticancer, and immune response modulation.
- Exhibits antineuroinflammatory activity by inhibiting NO production in LPS-induced mouse BV-2 cells
- Inhibits proliferation of DU145 prostate cancer cells
- Induces apoptosis in DU145 cells through ROS generation and mitochondrial apoptosis pathways
- Upregulates IL-8 and ICAM-1 expression
- Inhibits RANTES and MCP-1 release, showing immunomodulatory potential
- Significantly prevents *Vibrio anguillarum* infection in zebrafish embryos
- Increases embryo hatching rate in zebrafish models
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