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Apexbio Technology LLC Phenformin HCl 834-28-6 10mM (in 1mL DMSO)
Supplier: Apexbio Technology LLC B13735.1
Phenformin HCl (CAS 834-28-6) is the hydrochloride salt form of phenformin a biguanide-class compound exhibiting antidiabetic activity Phenformin acts primarily by reducing blood glucose levels and diminishing glycosuria as demonstrated in clinical studies with diabetic patients In an investigation involving five diabetic subjects treatment with phenformin led to notably decreased fasting blood glucose concentrations and urinary glucose excretion additionally cholesterol and total lipid levels reduced in four of the five patients studied Phenformin showed no measurable effect on glucose or insulin responses following intravenous glucose administration This biguanide derivative serves as an important pharmacological tool in diabetes-related biomedical research
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