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Medchemexpress LLC Phenformin (hydrochloride) | 834-28-6 | 99.6% | 241.72 | 1 G
Supplier: Medchemexpress LLC 1GHY16397A
Phenformin hydrochloride is an anti-diabetic agent belonging to the biguanide class, known for its ability to activate AMPK activity. It stimulates the phosphorylation and activation of both AMPKalpha1 and AMPKalpha2 without altering LKB1 activity, and has been shown to increase AMPK activity and phosphorylation in isolated hearts, correlated with increased cytosolic [AMP].
- Activates AMPK activity
- Targets AMPK
- Inhibits mitochondrial complex I more potently than metformin
- Induces apoptosis in LKB1 deficient NSCLC cell lines
- Appears as a white to off-white solid
- High purity of 99.6%
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