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Medchemexpress LLC Phenoxybenzamine hydrochloride | 63-92-3 | 99.5% | 25 MG
SDP

Supplier:  Medchemexpress LLC 25MGHYB0431AR

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Phenoxybenzamine hydrochloride is a nonselective, irreversible, orally active α-adrenoceptor antagonist commonly used for hypertension research, particularly for pheochromocytoma. It also demonstrates antitumor activity.

  • Inhibits U251 and U87MG cell proliferation.
  • Inhibits migration and invasion of U251 and U87MG cells.
  • Activates LINGO-1 and inhibits the TrkB-Akt pathway.
  • Prevents hippocampal cell death after oxygen glucose deprivation.
  • Shows anti-tumorigenic effect in nude mice with U87MG tumors.
  • Neuroprotective in a rat model of severe traumatic brain injury.

Catalog No. 50-004-50568


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