Phenyl isothiocyanate, 97%, Thermo Scientific Chemicals

Description

Phenyl isothiocyanate acts as a derivatizing reagent for primary and secondary amines. It is used in sequencing peptides by Edman degradation and in amino acid analyses by HPLC. It is used for derivatizing N-terminal amino acids of proteins for automated sequential analysis. It is a synthon for dithiadiazafulvalenes.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Phenyl isothiocyanate acts as a derivatizing reagent for primary and secondary amines. It is used in sequencing peptides by Edman degradation and in amino acid analyses by HPLC. It is used for derivatizing N-terminal amino acids of

Specifications

Chemical Identifiers

• CAS: 103-72-0
• Molecular Formula: C7H5NS
• Molecular Weight (g/mol): 135.18
• MDL Number: MFCD00004798
• InChI Key: QKFJKGMPGYROCL-UHFFFAOYSA-N
• Synonym: phenyl isothiocyanate, phenylisothiocyanate, thiocarbanil, phenyl mustard oil, benzene, isothiocyanato, pitc, isothiocyanic acid phenyl ester, benzene-1-isothiocyanate, phenylsenfoel, phenyl thioisocyanate
• PubChem CID: 7673
• ChEBI: CHEBI:85103
• IUPAC Name: isothiocyanatobenzene
• SMILES: S=C=NC1=CC=CC=C1

• Melting Point: -21°C
• Density: 1.131
• Boiling Point: 220°C to 221°C
• Flash Point: 87°C (188°F)
• Odor: Pungent
• Refractive Index: 1.65
• Quantity: 500 g
• UN Number: UN2927
• Beilstein: 471392
• Sensitivity: Moisture sensitive
• Merck Index: 14,7297
• Solubility Information: Soluble in alcohol,and ether. Insoluble in water.
• Formula Weight: 135.19
• Percent Purity: 97%
• Chemical Name or Material: Phenyl isothiocyanate

Safety and Handling

Hazard Category	H227-H301+H311+H331-H314-H317-H334-H335-H361d
Hazard Statement	GHS H Statement H301-H334-H314-H318-H227-H317; Toxic if swallowed. May cause allergy or asthma symptoms or breathing difficulties if inhaled. Causes severe skin burns and eye damage. Causes serious eye damage. Combustible liquid. May cause an allergic skin reaction.
Precautionary Statement	P201-P202-P210-P235-P260-P264b-P270-P271-P272-P280g-P281-P285-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P333+P313-P363-P370+P378q-P501c
DOTInformation	Transport Hazard Class: 6.1; Packing Group: II; Proper Shipping Name: TOXIC LIQUIDS, CORROSIVE, ORGANIC, N.O.S.
EINECSNumber	203-138-1
RTECSNumber	NX9275000
TSCA	Yes
Recommended Storage	Ambient temperatures; Store under Nitrogen

SDS

RUO – Research Use Only