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Medchemexpress LLC Phloretin | 60-82-2 | 99.92% | 274.27 | 50 G
Supplier: Medchemexpress LLC HYN014250G
Phloretin is a flavonoid extracted from *Malus pumila Mill.* that possesses anti-inflammatory activities. It is also a specific, competitive, and orally active inhibitor of sodium/glucose cotransporters in the intestine (SGLT1) and kidney (SGLT2). Phloretin inhibits Yeast-made GLUT1 and Human erythrocyte GLUT1 with IC50 values of 49 μM and 61 μM, respectively. It has potential for the treatment of rheumatoid arthritis (RA) and allergic airway inflammation.
- Possesses anti-inflammatory activities
- Inhibits SGLT1 and SGLT2
- Inhibits Yeast-made GLUT1 and Human erythrocyte GLUT1
- Potential for treating rheumatoid arthritis and allergic airway inflammation
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