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Cayman Chemical Phosphate Buffer 1ea
Supplier: Cayman Chemical 4000321 EA
An SGK1 inhibitor (IC50 600 nM) selective for SGK1 over c-Src and Abl kinases at 12.5 UM is cytotoxic to MCF-7 A172 and RKO cell lines at 12.5 UM reduces tumor volume tumor weight and SGK1 protein levels in a PDX mouse model of ovarian cancer at 9.3 mg/kg in combination with paclitaxel active against S. aureus and E. coli at 100 Ug/ml
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