U-Blot Phospho-c-Myc (Ser62) Rabbit mAb is a Rabbit-derived recombinant monoclonal antibody (clone W-R40) that specifically recognizes Phospho-c-Myc (Ser62) a phosphorylation modification at Ser62 It shows reactivity with Human Validated applications include WB Recommended dilutions WB 11000 Purified by protein a Myc also known as c-Myc together with l-Myc and n-Myc belongs to the Myc family of transcription factors Myc has a basic helix-loop-helix leucine zipper domain and through heterodimerization can bind and regulate the transcriptional activity of genes It is a key player in the regulation of cell growth and cell cycle progression and acts as a proto-oncogene Myc localizes to the nucleus but can also be present in the cytoplasm of certain cancer types Myc is ubiquitously expressed in almost all cell types and its expression positively correlates with tissue proliferative capacity Myc is also expressed during embryogenesis Supplied as 100 uL