U-Blot Phospho-Cardiac Troponin I (Ser23/24) Rabbit mAb is a Rabbit-derived recombinant monoclonal antibody (clone W-R36) that specifically recognizes Phospho-Cardiac Troponin I (Ser23/24) a phosphorylation modification at Ser23/24 It shows reactivity with Human Validated applications include WB Recommended dilutions WB 15000-110000 Purified by protein a Cardiac troponin is composed of three subunits namely cardiac troponin T (cTnT) cardiac troponin I (cTnI) and cardiac troponin C (cTnC) They collectively participate in the regulation of cardiac muscle contraction The amino-terminal and carboxyl-terminal ends of cTnI molecules are prone to degradation through protein hydrolysis Cardiac troponin I (cTnI) is an important regulatory factor that inhibits muscle contraction under normal circumstances It binds to actin preventing the interaction between actin and cardiac troponin C (cTnC) thus inhibiting muscle contraction Supplied as 100 uL