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Medchemexpress LLC Phospho-PKC zeta (Thr560) Antibody (YA162) | Protein A affinity purified | Predicted band size: 68 kDa; Observed band size: 75 kDa | 10 UL
Supplier: Medchemexpress LLC HYP8028010UL
PKC zeta is a calcium- and diacylglycerol-independent serine/threonine-protein kinase that operates in the PI3K pathway and MAP kinase cascade. It plays roles in NF-kappa-B activation, mitogenic signaling, cell proliferation, polarity, inflammatory responses, and long-term potentiation (LTP) maintenance. It also functions as an adaptor in insulin-dependent AKT3 activation, promoting SLC2A4/GLUT4 translocation and glucose uptake in adipocytes under insulin stimulation.
- Operates in PI3K pathway and MAP kinase cascade
- Involved in NF-kappa-B activation and mitogenic signaling
- Supports cell proliferation and polarity
- Contributes to inflammatory responses
- Essential for long-term potentiation (LTP) maintenance
- Promotes glucose uptake in adipocytes
- Mediates IL-1 signaling
- Drives neuronal differentiation
- Essential for Th2 differentiation
- Participates in long-term memory maintenance
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