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Medchemexpress LLC Phosphonoacetic acid | 4408-78-0 | 98.0% | 1 ML
SDP

Catalog No. 5000339996
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Phosphonoacetic acid is an endogenous metabolite and an antiviral agent. It exhibits activity against orthopoxviruses and herpes viruses. It can inhibit HSV DNA synthesis and virus-specific DNA polymerase activity, also affecting the synthesis of late viral proteins.

  • Active against orthopoxviruses and herpes viruses.
  • Inhibits HSV DNA synthesis.
  • Inhibits virus-specific DNA polymerase activity.
  • Affects the synthesis of late viral proteins.
  • IC50 & target: DNA polymerase, human endogenous metabolite.
  • Cellular effect: Vero CC50: 3500 μM, Vero ED50: 240 μM.
  • Inhibits viral growth and DNA synthesis in HSV-1-infected BHK-21 cells.
  • Shows protective effect in rabbit skin lesion model infected with orthopoxvirus.

Catalog No. 50-003-39996 Supplier Medchemexpress LLC Supplier No. HY12874410MM/1ML
May include imposed supplier surcharges.
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Phosphonoacetic acid is an endogenous metabolite and an antiviral agent. It exhibits activity against orthopoxviruses and herpes viruses. It can inhibit HSV DNA synthesis and virus-specific DNA polymerase activity, also affecting the synthesis of late viral proteins.

  • Active against orthopoxviruses and herpes viruses.
  • Inhibits HSV DNA synthesis.
  • Inhibits virus-specific DNA polymerase activity.
  • Affects the synthesis of late viral proteins.
  • IC50 & target: DNA polymerase, human endogenous metabolite.
  • Cellular effect: Vero CC50: 3500 μM, Vero ED50: 240 μM.
  • Inhibits viral growth and DNA synthesis in HSV-1-infected BHK-21 cells.
  • Shows protective effect in rabbit skin lesion model infected with orthopoxvirus.

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