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Apexbio Technology LLC Phosphoramidon Disodium Salt 164204-38-0 10mg

Supplier: Apexbio Technology LLC B479010
Phosphoramidon Disodium Salt (CAS 164204-38-0) is a metalloproteinase inhibitor targeting metalloenzyme activity implicated in endothelin biology Metalloproteinases rely on metal ions typically zinc for catalytic function Phosphoramidon interferes with the enzymatic conversion of big endothelin-1 (big ET-1) into endothelin-1 (ET-1) thereby decreasing ET-1 secretion while increasing levels of precursor peptides It reduces immunoreactive ET-1 release from porcine aortic endothelial cells and diminishes hypertensive responses triggered by big ET-1 in rodent models As such phosphoramidon serves as a valuable tool compound for cardiovascular and endothelin-related experimental research
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