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Medchemexpress LLC PHT-7.3 | 1614225-93-2 | 99.29% | 100 MG

Supplier: Medchemexpress LLC HY128590100MG
PHT-7.3 is a selective inhibitor of connector enhancer of kinase suppressor of Ras 1 (Cnk1) pleckstrin homology (PH) domain (Kd=4.7 μM). It inhibits mutant KRas, but not wild-type KRas cancer cell and tumor growth and signaling, demonstrating antitumor activity.
- Selective inhibitor of Cnk1 PH domain.
- Inhibits mutant KRas cancer cell and tumor growth.
- Demonstrates antitumor activity.
- Exhibits cytostatic antitumor activity in mut-KRas xenograft models.
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