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Cayman Chemical Phylnthus urnara Grn 10mg
Supplier: Cayman Chemical 2992410 MG
A tannin with diverse biological activities; scavenges DPPH (IC50s = 0.92 and 1.27 μM at pH 4.5 and 7.9, respectively), superoxide (IC50 = 2.65 μM), and hydroxyl radicals (IC50 = 1.44 μM) in cell-free assays; inhibits HSV-1 and HSV-2 replication in plaque reduction assays (IC50s = 35 and 18.4 μM, respectively); inhibits ACE (IC50 = 13.22 μM); reduces both systolic and diastolic blood pressure in spontaneously hypertensive rats at 5 mg/kg; induces apoptosis and halts the cell cycle at the S phase in A549 lung cancer cells at 5, 10, and 20 μM; reduces tumor growth in an A549 mouse xenograft model at 10 and 20 mg/kg
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