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Medchemexpress LLC Physalin A | 23027-91-0 | 99.6% | 526.53 | 1 MG
SDP

Catalog No. 5000425360
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Physalin A is a biologically active withanolide that demonstrates anti-inflammatory, antifibrotic, and ameliorative effects on autophagy in models of disc degeneration. It also exhibits antitumor activity by inducing apoptosis, ROS production, and G2/M phase cell cycle arrest, and can increase the activity of quinone reductase and the expression of detoxifying enzymes.

  • Demonstrates anti-inflammatory and antifibrotic effects
  • Ameliorates autophagy in disc degeneration models
  • Exhibits antitumor activity, inducing apoptosis and G2/M phase cell cycle arrest
  • Increases quinone reductase activity and detoxifying enzyme expression
  • Inhibits cell viability and induces apoptosis in human non-small cell lung cancer
  • Improves TGF-β1-induced fibrosis
  • Reduces inflammation via NF-κB and MAPK signaling pathway inhibition
  • Enhances autophagy by blocking PI3K/AKT/mTOR signaling pathways

Catalog No. 50-004-25360 Supplier Medchemexpress LLC Supplier No. HYN99421MG
May include imposed supplier surcharges.
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Physalin A is a biologically active withanolide that demonstrates anti-inflammatory, antifibrotic, and ameliorative effects on autophagy in models of disc degeneration. It also exhibits antitumor activity by inducing apoptosis, ROS production, and G2/M phase cell cycle arrest, and can increase the activity of quinone reductase and the expression of detoxifying enzymes.

  • Demonstrates anti-inflammatory and antifibrotic effects
  • Ameliorates autophagy in disc degeneration models
  • Exhibits antitumor activity, inducing apoptosis and G2/M phase cell cycle arrest
  • Increases quinone reductase activity and detoxifying enzyme expression
  • Inhibits cell viability and induces apoptosis in human non-small cell lung cancer
  • Improves TGF-β1-induced fibrosis
  • Reduces inflammation via NF-κB and MAPK signaling pathway inhibition
  • Enhances autophagy by blocking PI3K/AKT/mTOR signaling pathways

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