Phytohemagglutin-Leukoagglutinin, MP Biomedicals™

Description

Valuable in a wide variety of applications in vitro. Phytohemagglutin-Leukoagglutinin, MP Biomedicals is one of two molecular species of PHA. PHA-L has high mitogenic and leucoagglutinating activity, but very low erythroagglutinating activity.

PHA consists of two molecular species and two protein forms

• Erythroagglutinin (PHA-E) has low mitogenic activity and high erythroagglutinin activity. It is not blood group specific, but agglutination can be inhibited by certain oligosaccharides.
• Leucoagglutinin (PHA-L) has high mitogenic and leucoagglutinating activity, but very low erythroagglutinating activity.
• PHA-P is the protein form of PHA prior to separation and purification of erythroagglutinin and leucoagglutinin.
• PHA-M is the mucoprotein form.
• Conjugates are prepared from the corresponding purified lectins.

Reconstitute with water to a final concentration of 25mg/mL This concentration of the lectin has been used for iontophoresis and neuron transport. Phytohemagglutin is very valuable in a wide variety of applications in vitro, , including:

• Blood grouping and erythrocyte polyagglutination studies
• Mitogenic stimulation of lymphocytes
• Lymphocyte subpopulation studies
• Fractionation of cells and other particles
• Histochemical studies of normal and pathological conditions

Specifications

Chemical Identifiers

• Synonym: PHA-L, Phaseolus vulgaris agglutinin, PHA, PHA-P, Lectin from Phaseolus vulgaris

• Quantity: 1 mg
• Physical Form: Lyophilized Powder

Safety and Handling

Recommended Storage

−20°C

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