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Echelon Biosciences Research Labs PI(3,4,5)P3 DiC4 1 mg
Supplier: Echelon Biosciences Research Labs P39041MG
PI(3,4,5)P3 diC4 (Phosphatidylinositol 3,4,5-trisphosphate diC4) is a synthetic, purified dibutanoyl PI(3,4,5)P3.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3,4,5-trisphosphate (PIP3), formed from PI(4,5)P2 though phosphorylation by PI 3-kinase, activates numerous signaling pathways resulting in cell proliferation, growth, survival, glucose transport and protein synthesis. High PIP3 levels from disregulation of PI3-K have been demonstrated in cancer and inflammatory diseases. PIP3 is hydrolyzed by the phosphatases PTEN to PI(4,5)P2 and SHIP to PI(3,4)P2. This item is non returnable
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