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Echelon Biosciences Research Labs AS604850 (PI3-K gamma Inhibitor 2) 1 mg
SDP

Supplier:  Echelon Biosciences Research Labs B03021MG

Encompass

5-(2,2-Difluoro-benzo[1,3]dioxol-5-ylmethylene)-thiazolidine-2,4-dione (AS604850) is an inhibitor of PI 3-K with an IC50 = 250 nM. AS604850 is selective for the -isoform (IC50: PI 3-K = 4.5 M, PI 3-K, PI 3-K > 20 M) and shows no notable activity against a wide array of protein kinases at 1 M.nn

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Solubility

nWater: insoluble, DMSO: 5 mg/mLn

Storage

nStore dry between 2-8oC. Stock solutions should be stored frozen (-20oC).n

References

n1) M. Camps et al. "Blockade of PI3Kg suppresses joint inflammation and damage in mouse models of rheumatoid arthritis" Nature Medicine, 2005, 11, 936-943.nn
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Documents

nTechnical Data Sheet This item is non returnable

Catalog No. 50-720-014


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