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Echelon Biosciences Research Labs PI 3-Ka Inhibitor 2 5 mg

Supplier: Echelon Biosciences Research Labs B03045MG
3-(4-Morpholinothieno[3,2-d]pyrimidin-2-yl)phenol is a selective inhibitor for the -isoform of PI 3-Kinase (IC50: PI 3-K = 2 nM, PI 3-K = 16 nM, PI3-K = 660 nM, PI3KC2 = 220 nM)). It showed >1000-fold selectivity vs. protein kinases such as PKA, KDR, PKCa, and E/CDK2 (IC50 = 91, 3.4, 466, 288 M). It inhibited proliferation of A375 melanoma cells at 580 nM. This item is non returnable
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