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Apexbio Technology LLC PI-3065 955977-50-1 100mg
Supplier: Apexbio Technology LLC B4660100
PI-3065 (CAS 955977-50-1) is a selective small-molecule inhibitor targeting the phosphoinositide 3-kinase delta (PI3K ) isoform It exhibits potent inhibitory activity with reported Ki and IC50 values of approximately 1 5 nM and 5 nM respectively PI-3065 demonstrates marked selectivity showing significantly lower inhibitory potency against the related isoforms PI3K PI3K and PI3K In preclinical models treatment with PI-3065 suppressed growth and metastasis of 4T1 tumors extended survival and reduced tumor-related pathological outcomes This compound serves as a valuable tool for studying PI3K -driven signaling pathways in oncology and immunology research contexts
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