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Medchemexpress LLC PI-828 | 942289-87-4 | 99.6% | 322.36 | 25 MG
Supplier: Medchemexpress LLC 25MGHY108606
PI-828 is a dual inhibitor targeting both PI3K and casein kinase 2 (CK2). This compound demonstrates inhibitory activity against p110α, CK2, and CK2α2 in lipid kinase assays, making it suitable for various research applications.
- Dual inhibitor of PI3K and casein kinase 2 (CK2)
- IC50 of 173 nM for p110α
- IC50 of 149 nM for CK2
- IC50 of 1127 nM for CK2α2
- Shows cytotoxic effects on 4T1 breast and 4306 ovarian cancer cells
- Decreases caspase 3 activation and induces apoptosis in NCCIT cells
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