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Medchemexpress LLC PI-828 | 942289-87-4 | 99.62% | 322.36 | 100 MG
SDP

Supplier:  Medchemexpress LLC HY10860610MM/1ML

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PI-828 is a dual inhibitor of PI3K and casein kinase 2 (CK2) with IC50s of 173 nM for p110α, 149 nM for CK2, and 1127 nM for CK2α2 in a lipid kinase assay. It is intended for research use only.

  • Dual PI3K and casein kinase 2 (CK2) inhibitor.
  • Exhibits cytotoxic effect on 4T1 breast cancer cells and 4306 ovarian cancer cells.
  • Decreases caspase 3 activation at concentrations ranging from 0.78 to 3.12 μM; higher concentrations (6.25-12.5 μM) alone induce apoptosis.

Catalog No. 50-003-44807


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