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Medchemexpress LLC PI3K/Akt/CREB activator 1 | 2708177-73-3 | C19H15F4NO3 | 25 MG
Supplier: Medchemexpress LLC 25MGHY151527
PI3K/Akt/CREB activator 1 (compound AE-18) is a potent, orally active PI3K/Akt/CREB activator. It promotes neuronal proliferation, induces differentiation of Neuro-2a cells into a neuron-like morphology, and accelerates the establishment of axon-dendrite polarization of primary hippocampal neurons through upregulating brain-derived neurotrophic factor via the PI3K/Akt/CREB pathway. This product can be used in research of vascular dementia (VaD).
- Potent, orally active PI3K/Akt/CREB activator.
- Promotes neuronal proliferation.
- Induces differentiation of Neuro-2a cells into a neuron-like morphology.
- Accelerates axon-dendrite polarization of primary hippocampal neurons.
- Enhances neuronal differentiation and axon-dendrite polarization in cultured hippocampal neurons.
- Improves cerebral blood flow recovery and mitigates learning and memory impairment in chronic cerebral hypoperfusion animal models.
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