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Thermo Scientific™ Pierce™ Peptide Clean-Up Spin Tips
Description
Thermo Scientific™ Pierce™ Peptide Clean-Up Spin Tips are sorbent-based devices designed for rapid, reproducible peptide desalting, clean-up, and concentration prior to liquid chromatography-mass spectrometry (LC-MS) and other mass spectrometry (MS) workflows. These spin tips enable efficient peptide binding and recovery while removing salts, detergents, buffers, denaturants, chaotropes, and other chemistry-compatible contaminants that can interfere with downstream analysis. Available chemistries include octadecyl silica (C18), strong anion exchange (SAX), strong cation exchange (SCX), mixed-mode cation exchange (MCX), styrene divinylbenzene reversed-phase sulfonate (SDB-RPS), and styrene divinylbenzene crosslinked (SDB-XC), enabling selection based on the sample matrix, contaminant profile, and desired clean-up or fractionation strategy.
When used with Pierce™ Spin Tip adaptors (Catalog No. A40011776) and low protein binding microcentrifuge tubes (Catalog No. 90410), Thermo Scientific™ Pierce™ Peptide Clean-Up Spin Tips support a simple centrifugation-based workflow with standard laboratory equipment. The spin tip format provides a straightforward setup for peptide desalting, clean-up, concentration, or chemistry-compatible fractionation before downstream MS analysis.
Features of Thermo Scientific™ Pierce™ Peptide Clean-Up Spin Tips
- Efficient - help remove interfering contaminants to improve spectral quality and prepare peptide samples in mass spectrometry (MS)-compatible solutions
- Flexible - choose from multiple chemistries to support peptide desalting, clean-up, concentration, and fractionation strategies
- Convenient - process samples by standard centrifugation without specialized equipment using Pierce Spin Tip adaptors and low protein binding microcentrifuge tubes
Applications
- Peptide desalting prior to liquid chromatography-mass spectrometry (LC-MS) analysis
- Clean-up following enzymatic protein digestion workflows
- Removal of chemistry-compatible salts, buffers, detergents, denaturants, chaotropes, lipids, and other liquid chromatography-mass spectrometry (LC-MS) interferences
- Peptide concentration and mass spectrometry sample preparation
- Peptide fractionation to reduce sample complexity and support deeper proteome analysis
Specifications
Specifications
| Product Type | Spin Tip |
| Product Line | Pierce |
| Starting Material | Peptides, Protease-digested Protein |
| Detection Method | Mass Spectrometry |
| Format | Tip |
| Workflow Step | Peptide Clean-up |
| Quantity | 96 Tips |
| Form | Solid |
| Sorbent | SDB-XC |
For Research Use Only. Not for use in diagnostic procedures.
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