Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Thermo Scientific™ Pierce™ Streptavidin Magnetic Beads

Purify or immunoprecipitate biotinylated proteins or affinity ligands using streptavidin-coated magnetic particles for magnet-based separation.

Supplier:  Thermo Scientific™ 88817

 View more versions of this product

Catalog No. PI88817

Add to Cart



Accelerate throughput for automated magnetic purification of biotinylated molecules with Thermo Scientific™ Pierce Streptavidin Magnetic Beads.

Magnetic streptavidin beads enable affinity purification of biotin-labeled target molecules without columns or centrifugation. The platform provides a fast and convenient method for manual or automated immunoprecipitation, protein interaction analysis, DNA-protein pull-down, and purification involving biotin-labeled proteins and nucleic acids. The iron oxide superparamagnetic particles offer superior performance (high capacity and low nonspecific binding) compared with other commercial magnetic beads. Biotinylated molecules are simply added to the streptavidin-coated magnetic beads for binding. Pierce Streptavidin Magnetic Beads are validated and optimized for use with high-throughput magnetic platforms, such as the Thermo Scientific KingFisher™ 96 and KingFisher Flex Instruments, but the beads also enable premium performance for simple benchtop applications using an appropriate magnetic stand.


  • High-performance beads – non-aggregating, pre-blocked, iron oxide, superparamagnetic microparticles provide exceptional uniformity for automated HTS and manual applications alike

  • Stable immobilization chemistry – streptavidin is immobilized using leach-resistant chemistry

  • High capacity – superior quality beads with high binding capacity provide rapid and efficient biomolecule purification from complex samples

  • Low non-specific binding – stable, pre-blocked beads provide clean purification products (e.g., antigen eluted in IP with biotinylated antibody) that are compatible with mass spectrometry analysis and other downstream analyses

  • Superior performance – nearly three times higher binding capacity than typical beads from other suppliers, allowing the use of smaller amounts per experiment

Properties of Streptavidin Magnetic Beads:

  • Composition: ion oxide particles covalently coated with a monolayer of streptavidin protein
  • Magnetization: superparamagnetic (no magnetic memory)
  • Bead size: 1μm (nominal mean diameter)
  • Density: 2g/cm3
  • Concentration: 10mg beads per milliliter of slurry in 0.05% sodium azide
  • Binding capacity: approx. 55μg biotinylated rabbit IgG per mg of beads; approx. 3500pmol biotinylated fluorescein per milliliter of beads
  • RNase: these bead solutions are NOT tested and certified to be RNAse-free


Thermo Scientific KingFisher 96 or KingFisher Flex Instrument or other magnetic separator device

Recommended for:

Immunoprecipitate antigens (using biotinylated antibodies) from a wide variety of sources; Co-immunoprecipitate interaction complexes using biotinylated antibodies; Capture protein-protein interactions in pull-down assays using biotinylated bait proteins; Isolate biotin-labeled DNA-protein complexes from cell or tissue extracts; Capture single-stranded biotinylated DNA oligos; Isolate biotinylated PCR products



Upon receipt store at 4°C. Product is shipped on an ice pack.
Magnetic Affinity Bead
5 mL
Product Suggestions

Product Suggestions



Product Certifications


Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit

For Research Use Only. Not for use in diagnostic procedures.