Thermo Scientific™ Pierce™ Traut's Reagent (2-iminothiolane)

Description

2-Iminothiolane-HCl (CAS 4781-83-3); an amine-reactive thiolation reagent to cap protein primary amines with sulfhydryl groups for immediate crosslinking.

Thermo Scientific™ Pierce Traut's Reagent is 2-iminothiolane, a small thiolation compound that reacts with primary amines (e.g., lysine side chains) to add a small spacer arm (8.1 Ås) terminated by a free sulfhydryl group.

Highlights:

• Reacts with primary amines (lysine epsilon amino groups) at pH 7-9
• Adds a short spacer ending in a sulfhydryl group, ready for use as a target for sulfhydryl-specific crosslinking or labeling
• Amine-containing spacer arm preserves charge of original, modified primary amine

Specifications

• Chemical Reactivity: Amine
• Content And Storage: Storage: Upon receipt store product at 4°C with desiccant. Product shipped at ambient temperature
• Label or Dye: Sulfhydryl Group
• Label Type: Conjugating Groups
• Product Line: Pierce™
• Spacer: Short (<10 Å)
• Form: Powder
• Quantity: 500 mg
• Solubility: DMF, DMSO
• Product Type: Thiophilic Adsorption Kit

For Research Use Only. Not for use in diagnostic procedures.