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TARGETMOL CHEMICALS INC PIFITHRIN-BETA HYDROBROM 25MG
SDP

Supplier:  TARGETMOL CHEMICALS INC T363725MG

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Also available in 2 mg 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Pifithrin-(beta) hydrobromide (Cyclic PFT-(alpha)) is an inhibitor of p53; reversibly blocks p53-dependent transcriptional activation and apoptosis. Protects against neuronal death in models of stroke and neurodegenerative disorders. Active in vivo; protects mice from the side-effects of Y therapy associated with p53 induction. Supresses self-renewal of embryonic stem cells. Also aryl hydrocarbon receptor (AHR) agonist causes upregulation of AHR target gene CYP1A1 (EC50 = 1.1 uM). purity: 99%

Catalog No. 50-258-0186


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