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Medchemexpress LLC Pifithrin-β hydrobromide | 511296-88-1 | 99.9% | 349.29 | 1 ML
Supplier: Medchemexpress LLC HY16702A10MM/1ML
Pifithrin-β hydrobromide is a potent p53 inhibitor with an IC50 of 23 μM. It is regarded as a lead compound for cancer and neurodegenerative disease therapy. Pifithrin-α, an inhibitor of the p53 protein, is unstable in culture medium and quickly converts to pifithrin-β. Studies show that pretreatments with 1 and 10 μM pifithrin-β can exert neuroprotective effects after 24 hours.
- Potent p53 inhibitor with an IC50 of 23 μM.
- Regarded as a lead compound for cancer and neurodegenerative disease therapy.
- Exerts neuroprotective effects.
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