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Apexbio Technology LLC PIK-93 593960-11-3 100mg
Supplier: Apexbio Technology LLC A5449100
PIK-93 (CAS 593960-11-3) is a small-molecule inhibitor targeting PI3K (p110 ) and PI4KIII It is designed to inhibit these kinases thereby modulating phosphoinositide signaling pathways involved in cellular proliferation migration survival intracellular trafficking and membrane dynamics PIK-93 exerts its biological activity through inhibition of PI3K and PI4KIII In cell-based studies PIK-93 demonstrates potent inhibitory activity with IC50 values of 16 nM for PI3K and 19 nM for PI4KIII It also exhibits antiviral activity against poliovirus replication with an EC50 of 0 14 M in PV pseudovirus infection assays Based on these pharmacological properties PIK-93 holds research potential in the study of PI3K/PI4K-mediated cellular signaling oncology and mechanisms of viral replication
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